In vitro and in vivo antivirus activity of an anti-programmed death-ligand 1 (PD-L1) rat-bovine chimeric antibody against bovine leukemia virus infection.
Programmed death-1 (PD-1), an immunoinhibitory receptor on T cells, is known to be involved berness white sneakers in immune evasion through its binding to PD-ligand 1 (PD-L1) in many chronic diseases.We previously found that PD-L1 expression was upregulated in cattle infected with bovine leukemia virus (BLV) and that an antibody that blocked the P